213966

Eczema Biopsy Study

Study Summary

You are invited to participate in a research study.  The purpose of you taking part in this clinical procedure is to provide fresh tissue biopsy samples for use in an external research study.

You will be required to attend 1 visit to the test centre.

First, you will go through the screening procedures to see if you qualify to participate in study.  For this study and to be eligible to take part in the clinical procedure you must be in good general health and be aged 18-50. You must have previously had a diagnosis of atopic dermatitis (Eczema) and have active atopic dermatitis with visible areas on your body.

If eligible the biopsy sampling procedure will be performed. You will have 2 biopsies performed on 2 different areas on your body. The desired suture type for this study is dissolvable which requires no further visit to the test centre; however, during the procedure the Doctors may use non-dissolvable sutures, if medically required. If this is the case, you will be invited back for a 2nd visit to remove the sutures and will receive an additional expenses cheque for £10.

Attendance 1 Visit

You will be required to attend ONE Visit below. - This visit will take 1 hour and 45 minutes.

Monday 28 October 2019 – appointments available between 8:30am – 2pm.
OR
Monday 04 November 2019 - appointments available between 8:30am – 2pm.

Please note there may be additional visits available awaiting medic confirmation so please let us know if you are interested but cannot attend the visit above.

Inclusion Criteria

Inclusion Criteria

Male or Females.

Caucasian.

Aged 18 – 50.

Able to communicate well with the investigator.

Provision of written informed consent to participate as shown by a witnessed signature on the subject consent form.

Suitable biopsy sites, moderate to severe as assessed by the study medic.

Exclusion Criteria

Exclusion Criteria

Those suffering from any blood borne viruses e.g. HIV, Hepatitis.

Those suffering from any medical condition which, in the opinion of the test personnel, will automatically exclude them from participating in the study.

Those who have participated in a similar study in the last month.

Any allergy to xylocaine and adrenaline.

Any history of delayed or problems with wound healing e.g. keloid scars.

Pregnant or nursing (lactating) women.

Those regularly taking antihistamines.

Those who have applied any topical products including emollients to the biopsy site within 48 hours of study visit.

Those who have used systemic steroids within 6 weeks of study visit.

Those who have used oral anti-inflammatory drugs within 2 weeks of study visit.

Those who have used topical steroids within 1 week of study visit.

Those treated with biologics or oral steroids within 6 weeks of study visit.

Those with disease present only on hands would not be accepted onto the study.

Study Restrictions

Study Restrictions

Donors are advised to refrain from using ibuprofen and Aspirin 24 hours prior to and after the procedure as these medicines may make the wound ooze more. If the donor required to take a pain medication paracetamol is recommended.

Donors are advised to keep the wound dry for the first 48 hours. If the dressing gets wet, they should apply Vaseline (provided by alba) to the sites and replace with a dry breathable dressing.

Donors are advised that after 48 hours it is better to leave the wound uncovered unless clothing irritates the area or there is discharge from the wound.

Donors are advised to avoid swimming, heavy lifting and sports while their stitches are in place and take care for a couple of weeks after they have been removed.

Expenses

You will receive £125 expenses on completion of your biopsy visit.

This will be paid in a cheque in your name.

How to Apply

To take part in this study please reply to this email.

213901

Spot Study

Study Summary

Alba Science would like to invite you to participate in a spot study using a facial lotion to assess the efficacy and tolerance of the facial lotion in reducing skin imperfections associated with acne/ spots under normal use conditions.  Efficacy and tolerance will be determined by expert assessment and consumer perception following 4 weeks of product use (twice daily applications).  Skin tolerance of the facial lotion will be evaluated according to the results of the objective and subjective data.

Approximately 100 female volunteers with oily spot prone skin will be recruited. 

The objective of the study is to evaluate the in-use efficacy and tolerance of the Facial Lotion on female subjects when applied to the face twice daily, for 4 weeks.  Skin evaluations will be performed by a Dermatology Consultant at Screening, Baseline, Week 1 and Week 4.  In addition, lesion counts will be repeated following a one-week and week 5.  Freshness effect will be evaluated immediately following the first application of the test material using a scale completed by the Subject under supervision from test personnel.  Consumer questionnaire will be completed immediately following the first application of the test material, and at the Week 1, Week 4 and Week 5 assessments.

On return to visit 2 if you are not suitable to carry on with the study you will receive £25 expenses,  if you complete all 5 visits you will receive £100 expenses.

Attendance – 5 Visits

You will be required to attend 5 visits in total to complete this study, 1 screening visit and 4 main study visits,  all visits will take approx. 1 hour and 30 minutes each.

Screening Visits (Please Choose from ONE of the visits below)

Tuesday 29 October 2019

This visit will take approx. 1 hour and 30 minutes.

Appointments will run between 9am – 4pm

Wednesday 30 October 2019

This visit will take approx. 1 hour and 30 minutes.

Appointments will run between 9am – 3:30pm

Thursday 31 October 2019

This visit will take approx. 1 hour and 30 minutes.

Appointments will run between 9am – 4pm

Friday 01 November 2019

This visit will take approx. 1 hour and 30 minutes.

Appointments will run between 9am – 4pm

Main Study

Group 1

Visit

Study Dates

Approx. Length of Study Visit

Appointment Times

Visit 2

Tuesday 12 November 2019

Approx. 1 Hour & 30 Minutes

Appointments will run between 9am – 4pm

Visit 3

Tuesday 19 November 2019

Approx. 1 Hour & 30 Minutes

Appointments will run between 9am – 4pm

Visit 4

Tuesday 10 December 2019

Approx. 1 Hour & 30 Minutes

Appointments will run between 9am – 4pm

Visit 5

Tuesday 17 December 2019

Approx. 1 Hour  & 30 Minutes

Appointments will run between 9am – 4pm

OR

Group 2

Visit

Study Dates

Approx. Length of Study Visit

Appointment Times

Visit 2

Friday 15 November 2019

Approx. 1 Hour & 30 Minutes

Appointments will run between 9am – 4pm

Visit 3

Friday 22 November 2019

Approx. 1 Hour & 30 Minutes

Appointments will run between 9am – 4pm

Visit 4

Friday 13 December 2019

Approx. 1 Hour & 30 Minutes

Appointments will run between 9am – 4pm

Visit 5

Friday 20 December 2019

Approx. 1 Hour  & 30 Minutes

Appointments will run between 9am – 4pm

Inclusion Criteria

Subjects Must Be:

Healthy Female.

Aged 18-40 years.

Must be Fitzpatrick skin types II – III.

Have oily skin (determined by Dermatology Consultant assessment).

Subjects presenting with visible imperfections on the face e.g. open pores, clogged pores, pimples, blackheads. Imperfections will be visualized by Dermascore device.

Subjects with at least 10 retentional lesions and 5 inflammatory lesions (pustules, papules).

Subjects presenting a dull complexion.

Subjects willing to use the facial lotion in place of their usual Facial Lotion.

Subjects are taking an effective oral contraception or other method of contraception.

Subjects are willing to refrain from using any cosmetic for oily skin/ regulation of sebum and acne for the duration of the study.

Able to communicate well with the investigator and to comply with the requirements of the entire study.

Provision of written informed consent to participate as shown by a witnessed signature on the Subject Consent Form.

Exclusion Criteria

You will not be eligible to take part in this study if any of the following applies:

Those who are pregnant or breastfeeding.

Those who are medications, including antibiotics, which in the opinion of the test personnel may affect the test results.

Those suffering from any medical condition which, in the opinion of the test personnel, will automatically exclude them from participating in the study.

Those with an active skin disease or skin disorder (psoriasis, eczema, scars, wounds, active herpes or systemic infection) that could influence with the study evaluation or could require local or systemic therapy.

Those who have undergone surgical or non-surgical aesthetic procedures in the last 12 months (e.g. botox, fillers, chemical or mechanical peeling, dermabrasion, laser, pulsed light etc.)

Those who have received injections to the face for either medical or cosmetic purpose in the 6 months preceding to the start of the study.

Those who have taken an oral retinoid-based treatment in the last 6 months.

Those who have started, changed or discontinued hormonal treatment (combined oestrogen/progestin or cyproterone acetate) in the 3 months preceding to the start of the study.

Those who have received anti-acne and anti-seborrheic medical treatment (oral and topical) in the last 2 months.

Those who have used a topical retinoid treatment in the last 2 months.

Those who have performed facial aesthetic care at home or have received facial aesthetic care in a beauty salon (such as exfoliating scrub, mask) in the last month.

Those who have had an allergic reaction to a cosmetic product.

Those who have applied any products on their face (skin care or cleanser) or shampoo for 24 hours prior to the first product application at Visit 2.

Those who have used cosmetic products on assessment days (only water for cleansing face on the day of a test Centre visit).

  

Study Restrictions

Volunteers will be requested to observe the following restrictions during the course of their participation in the study:

Not to use aspirin, anti-inflammatory drugs, anti-histamines or corticosteroids for the duration of the study (paracetamol is permissible for pain relief). Subjects are requested to alert test personnel of any changes to medication during this study and are informed that certain medications may fall within the exclusion criteria, and may result in their withdrawal from the study.

Not to change your regular brands of other facial skincare products including cleansers and make up during the study.

To attend the test Centre visits having refrained from applying any products to your face.

To refrain from washing hair on the evening prior to and the morning of all test center visits.

Expenses

You will receive a cheque for £100 in your name on completion of this study.

How to Apply

To take part in this study please email recruitment@albavolunteers.com.

Alba Science invites you to take part in a research study for parents/guardians with children between the ages of 0-36 months who are responsible for the application of personal care products on their child.

This study aims to assess which personal care products (baby as well as family products) parents use on their child and which quantity and which context (e.g.: type of personal care products used, times of day products are applied, area of product application,  general usage frequency of personal care products)

This study is being conducted without any treatment or intervention; it is merely for the collection of usage data.

Please note: This study will require 2 visits to the Alba Science test centre, which is located at 24 Broughton Street, Edinburgh, EH1 3RH.

 

The following study groups are currently available:

Group 5

Visit 1 - Monday 28 October 2019
Visit 2 - Monday 04 November 2019

 

Group 6

Visit 1 - Tuesday 29 October 2019
Visit 2 - Tuesday 05 November 2019

 

Group 7

Visit 1 - Wednesday 30 October 2019
Visit 2 - Wednesday 06 November 2019

 

Group 8

Visit 1 - Thursday 31 October 2019
Visit 2 - Thursday 07 November 2019

 

Expenses: You will be given a £70 cheque in your name on completion of this study.

If you are interested in taking part in this study, please read the study inclusions and exclusions listed below.

STUDY INCLUSIONS

In order to take part in this study, volunteers must:

·          Be a Parent (Mother, Father or Legal Guardian) with a child 0-36 months.  Age verification of the child will be performed by checking government issued identification (e.g.            passport or birth certificate) during screening.

·        Be a Parent (Mother, Father or Legal Guardian) who is at least partially responsible for the application of personal care products on their child.

·        Be a Parent (Mother, Father or Legal Guardian) who regularly uses/applies personal care products (i.e. baby cream, baby shampoo, soap, etc) to their child.

·        Be willing to continue normal usage of each type of product with no change from normal regime or frequency.

·        Be a Parent (Mother, Father or Legal Guardian) who is willing to attend both appointments with all personal care products that they intend to use on their child during the duration   of the study.

·        Be a Parent (Mother, Father or Legal Guardian) who is willing to complete each relevant diary sheet after each individual product usage.

·        Be a Parent (Mother, Father or Legal Guardian) who is able to communicate well with the investigator and to comply with the requirements of the entire study. 

·        Provide written informed consent to participate as shown by a witnessed signature on the Subject Consent Form.

STUDY EXCLUSIONS

You will NOT be eligible for this study if any of the following applies:

·        Child is taking part in any other clinical or usage study.

·        Parent/guardian is unable to provide proof of age for the child.

·        Parent/guardian and child will be on holiday (away from home) during the study period.

·        Child is in day care for more than 3 hours per day.

·        Child spends large quantities of time not in the primary care of parent/guardian subject (i.e. staying with family members/care providers overnight or for extended periods.)

 

If you are interested in taking part in this study please email recruitment@albavolunteers.com or call 08007561046.